Table 6 Genotype results for GIPR SNP rs2302382 in the population-based cohorts KORA and SHIP
Group | genotypes, n (frequency) | Allele frequency | effect size estimate (95%CI)1 | p-value1 | ||||
|---|---|---|---|---|---|---|---|---|
CC | CA | AA | C | A | ||||
KORA | BMI ≥ 30 kg/m2 | 1,103 (0.597) | 644 (0.348) | 102 (0.055) | 0.771 | 0.229 | βA 0.12 | 0.136 |
BMI <30 kg/m2 | 3,993 (0.622) | 2,117 (0.330) | 310 (0.048) | 0.787 | 0.213 | (-0.04; 0.28) | ||
SHIP | BMI ≥ 30 kg/m2 | 645 (0.640) | 332 (0.329) | 31 (0.031) | 0.805 | 0.195 | βA -0.27 (-0.52; -0.24) | 0.031 |
BMI <30 kg/m2 | 1,842 (0.622) | 995 (0.336) | 126 (0.042) | 0.790 | 0.210 | |||