Table 2 Odds Ratios for Colorectal Cancers and Colorectal Adenomas including high- and low-risk adenomas for MDR1 G-rs3789243-A
NCase | NControl | ORa | 95% CI | ORb | 95% CI | |
|---|---|---|---|---|---|---|
Colorectal Cancer | ||||||
GG | 50 | 101 | 1.00 | - | 1.00 | - |
GA | 78 | 190 | 0.80 | (0.53–1.22) | 0.79 | (0.44–1.41) |
AA | 39 | 104 | 0.73 | (0.45–1.20) | 0.55 | (0.27–1.12) |
GA and AA | 117 | 294 | 0.78 | (052–1.15) | 0.70 | (0.41–1.21) |
Colorectal Adenomas | ||||||
GG | 253 | 101 | 1.00 | - | 1.00 | - |
GA | 482 | 190 | 1.01 | (0.76–1.35) | 0.98 | (0.73–1.35) |
AA | 234 | 104 | 0.90 | (0.65–1.24) | 0.93 | (0.65–1.33) |
GA and AA | 716 | 294 | 0.97 | (0.74–1.27) | 0.96 | (0.72–1.29) |
High-risk adenomas | ||||||
GG | 61 | 101 | 1.00 | - | 1.00 | - |
GA | 109 | 190 | 0.95 | (0.64–1.41) | 1.08 | (0.69–1.70) |
AA | 54 | 104 | 0.86 | (0.54–1.36) | 0.98 | (0.58–1.64) |
GA and AA | 163 | 294 | 0.92 | (0.63–1.33) | 1.04 | (0.68–1.59) |
Low-risk adenomas | ||||||
GG | 192 | 101 | 1.00 | - | 1.00 | - |
GA | 373 | 190 | 1.03 | (0.77–1.39) | 0.98 | (0.71–1.36) |
AA | 180 | 104 | 0.91 | (0.65–1.28) | 0.93 | (0.64–1.36) |
GA and AA | 553 | 294 | 0.99 | (0.75–1.31) | 0.97 | (0.71–1.32) |