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Figure 1 | BMC Medical Genetics

Figure 1

From: PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism

Figure 1

Detection of PRNP polymorphisms. Panels A and B: Genotyping by PCR amplification of PRNP and restriction enzyme digest. (Mw: 100 bp molecular weight ladder (dark band 600 bp); MV, MM, VV: codon 129 genotypes; WT: wild-type codon 117 genotype; MUT: heterozygous for codon 117 polymorphism) Panels C, D, and E: Electropherograms for polymorphisms detected by sequence analysis. (Arrows point to heterozygous base position.)

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