Table 2 AFM/IL8 haplotype frequency estimates in cases and controls and risk estimates from CLR analysis of matched case-control pairs.
Haplotype a | # controls | freq | # cases(TS) | freq | p-value | CLR:OR (95%CI) | # controls | freq | # cases(TT) | freq | p-value | CLR:OR (95%CI) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AGGTAGTAC | 215 | 0.35 | 195 | 0.34 | - | reference | 162 | 0.35 | 152 | 0.36 | - | reference |
GAATATTAC | 79 | 0.13 | 108 | 0.19 | 0.061 | 1.42 (0.98, 2.04) | 55 | 0.12 | 75 | 0.18 | 0.150 | 1.38 (0.89, 2.13) |
AGGTATTAC | 64 | 0.10 | 38 | 0.07 | 0.037 | 0.59 (0.36, 0.97) | 49 | 0.11 | 32 | 0.08 | 0.113 | 0.62 (0.35, 1.12) |
GAATAGTAC | 50 | 0.08 | 51 | 0.09 | 0.453 | 1.20 (0.75, 1.90) | 38 | 0.08 | 35 | 0.08 | 0.553 | 1.19 (0.68, 2.08) |
GGGTAGTAC | 50 | 0.08 | 42 | 0.07 | 0.829 | 0.94 (0.57, 1.58) | 33 | 0.07 | 28 | 0.07 | 0.489 | 0.79 (0.41, 1.53) |
GGATATTAC | 39 | 0.06 | 23 | 0.04 | 0.127 | 0.62 (0.34, 1.15) | 26 | 0.06 | 20 | 0.05 | 0.420 | 0.75 (0.38, 1.50) |
AGGTTTTAA | 33 | 0.05 | 23 | 0.04 | 0.323 | 0.74 (0.40, 1.35) | 28 | 0.06 | 16 | 0.04 | 0.067 | 0.50 (0.24, 1.05) |
AGGCAGTAC | 23 | 0.04 | 26 | 0.05 | 0.597 | 1.18 (0.63, 2.22) | 19 | 0.04 | 20 | 0.05 | 0.984 | 1.01 (0.49, 2.06) |
GGACAGTAC | 26 | 0.04 | 17 | 0.03 | 0.356 | 0.73 (0.38, 1.42) | 20 | 0.04 | 13 | 0.03 | 0.469 | 0.75 (0.35, 1.62) |
AGGCATTAC | 26 | 0.04 | 30 | 0.05 | 0.229 | 1.48 (0.78, 2.80) | 17 | 0.04 | 22 | 0.05 | 0.286 | 1.50 (0.71, 3.15) |
GAATTTTAA | 14 | 0.02 | 18 | 0.03 | 0.413 | 1.39 (0.63, 3.03) | 12 | 0.03 | 10 | 0.02 | 0.892 | 0.93 (0.35, 2.49) |
others | 145 | 0.23 | 157 | 0.27 | - | - | 97 | 0.21 | 115 | 0.27 | - | - |