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Table 2 AFM/IL8 haplotype frequency estimates in cases and controls and risk estimates from CLR analysis of matched case-control pairs.

From: Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians

Haplotype a # controls freq # cases(TS) freq p-value CLR:OR (95%CI) # controls freq # cases(TT) freq p-value CLR:OR (95%CI)
AGGTAGTAC 215 0.35 195 0.34 - reference 162 0.35 152 0.36 - reference
GAATATTAC 79 0.13 108 0.19 0.061 1.42 (0.98, 2.04) 55 0.12 75 0.18 0.150 1.38 (0.89, 2.13)
AGGTATTAC 64 0.10 38 0.07 0.037 0.59 (0.36, 0.97) 49 0.11 32 0.08 0.113 0.62 (0.35, 1.12)
GAATAGTAC 50 0.08 51 0.09 0.453 1.20 (0.75, 1.90) 38 0.08 35 0.08 0.553 1.19 (0.68, 2.08)
GGGTAGTAC 50 0.08 42 0.07 0.829 0.94 (0.57, 1.58) 33 0.07 28 0.07 0.489 0.79 (0.41, 1.53)
GGATATTAC 39 0.06 23 0.04 0.127 0.62 (0.34, 1.15) 26 0.06 20 0.05 0.420 0.75 (0.38, 1.50)
AGGTTTTAA 33 0.05 23 0.04 0.323 0.74 (0.40, 1.35) 28 0.06 16 0.04 0.067 0.50 (0.24, 1.05)
AGGCAGTAC 23 0.04 26 0.05 0.597 1.18 (0.63, 2.22) 19 0.04 20 0.05 0.984 1.01 (0.49, 2.06)
GGACAGTAC 26 0.04 17 0.03 0.356 0.73 (0.38, 1.42) 20 0.04 13 0.03 0.469 0.75 (0.35, 1.62)
AGGCATTAC 26 0.04 30 0.05 0.229 1.48 (0.78, 2.80) 17 0.04 22 0.05 0.286 1.50 (0.71, 3.15)
GAATTTTAA 14 0.02 18 0.03 0.413 1.39 (0.63, 3.03) 12 0.03 10 0.02 0.892 0.93 (0.35, 2.49)
others 145 0.23 157 0.27 - - 97 0.21 115 0.27 - -
  1. a Haplotype configuration: AFP+8865, AFM+1666, AFM+4530, AFM+15790, IL8-251, IL8+396, IL8+37674, IL8+39739, IL8+40050. Others refers to population haplotypes of <10% frequency.