STK39 polymorphisms and blood pressure: an association study in British Caucasians and assessment of cis-acting influences on gene expression

Table 3 Effect sizes of tested SNPs

BP phenotype*	N	rs3754777	rs35929607	rs6749447	rs4977950
Clinic Systolic	1138	0.2 (-1.8, 2.3)	1 (-1, 2.9)	0.5 (-1.2, 2.2)	0 (-2.1, 2.1)
Clinic Diastolic	1130	-0.3 (-1.6, 1.1)	0.4 (-0.9, 1.7)	0.1 (-1, 1.2)	0.3 (-1.1,1.7)
Day Systolic	1134	-0.1 (-1.9, 1.7)	-0.3 (-1.5, 2)	0.1 (-1.4, 1.6)	0.2 (-1.7, 2)
Day Diastolic	1133	-0.1 (-1.4, 1.1)	0.2 (-1, 1.4)	0.1 (-0.9, 1.2)	0.4 (-0.9, 1.7)
Night Systolic	903	0.4 (-1.4, 2.1)	0.9 (-0.8, 2.6)	0.7 (-0.7, 2.2)	-0.2 (-2.1, 1.7)
Night Diastolic	902	0.7 (-0.5, 1.9)	1.1 (0, 2.3)	0.8 (-0.2, 1.8)	-0.1 (-1.3, 1.2)

* All phenotypes log-transformed to approximately normalise distributions and adjusted for covariates before analysis; Effect sizes are the mmHg difference attributable to 1 copy of the risk (minor) allele, with 95% confidence interval given in brackets. P-value > 0.05 for all effects.

ISSN: 1471-2350