STK39 polymorphisms and blood pressure: an association study in British Caucasians and assessment of cis-acting influences on gene expression

Table 2 Allele frequencies of the SNPs typed in study participants

SNP	Chromosome location	Alleles*	Number genotyped	HW P-value	Frequency of putative risk allele
					Caucasian cohort	HapMap CEU	SA cohort
rs3754777	2q24 (STK39 intron)	G/A	1367	0.63	0.17	0.13	0.16
rs35929607	2q24 (STK39 intron)	A/G	1361	0.79	0.19	NA	0.34
rs6749447	2q24 (STK39 intron)	T/G	1369	0.32	0.29	0.28	0.52
rs4977950	9p21 (not within gene)	G/C	1365	0.46	0.15	0.18	NA

* Major allele given first, putative risk allele for hypertension identified by Wang et al shown in bold; MAF, minor allele frequency; CEU, HapMap CEU Caucasian cohort; NA, not available; SA, South African.

ISSN: 1471-2350