| Controls (n = 176) | COPD (n = 599) | Additive | Recessive | Dominant | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | 0 | 1 | 2 | 0 | 1 | 2 | p-value | Odds ratio | 95%CI | p-value | Odds ratio | 95%CI | p-value | Odds ratio | 95%CI |
rs4803648 | 112 | 48 | 9 | 381 | 180 | 21 | 0.963 | 1.01 | 0.70-1.45 | 0.313 | 0.60 | 0.23-1.61 | 0.637 | 1.11 | 0.72-1.70 |
rs4802189 | 117 | 47 | 4 | 420 | 151 | 12 | 0.964 | 0.99 | 0.66-1.48 | 0.735 | 0.79 | 0.20-3.13 | 0.955 | 1.01 | 0.65-1.59 |
rs4251953 | 158 | 15 | 1 | 540 | 43 | 2 | 0.800 | 0.92 | 0.49-1.74 | 0.825 | 1.38 | 0.08-24.45 | 0.742 | 0.89 | 0.45-1.77 |
rs4251938 | 133 | 38 | 1 | 466 | 116 | 8 | 0.969 | 0.99 | 0.63-1.56 | 0.656 | 1.70 | 0.17-17.27 | 0.883 | 0.96 | 0.59-1.57 |
rs4251923 | 166 | 8 | 0 | 544 | 44 | 0 | 0.598 | 1.28 | 0.52-3.16 | ND | ND | ND | 0.598 | 1.28 | 0.52-3.16 |
rs4760 | 122 | 38 | 10 | 429 | 146 | 13 | 0.271 | 0.81 | 0.56-1.18 | 0.106 | 0.42 | 0.15-1.20 | 0.523 | 0.86 | 0.55-1.36 |
rs2302524 | 121 | 54 | 1 | 422 | 149 | 16 | 0.691 | 0.92 | 0.63-1.37 | 0.081 | 7.23 | 0.78-66.86 | 0.293 | 0.79 | 0.51-1.22 |
rs4251864 | 143 | 30 | 1 | 507 | 81 | 5 | 0.976 | 1.01 | 0.61-1.66 | 0.480 | 2.38 | 0.22-26.30 | 0.876 | 0.96 | 0.56-1.64 |
rs2239372 | 48 | 84 | 41 | 150 | 284 | 156 | 0.679 | 1.06 | 0.80-1.40 | 0.857 | 1.04 | 0.66-1.66 | 0.621 | 1.12 | 0.71-1.76 |
rs2283628 | 122 | 43 | 10 | 396 | 172 | 23 | 0.822 | 0.96 | 0.67-1.38 | 0.118 | 0.47 | 0.18-1.21 | 0.706 | 1.09 | 0.71-1.67 |
rs4251846 | 141 | 31 | 3 | 452 | 134 | 8 | 0.518 | 1.16 | 0.74-1.82 | 0.380 | 0.50 | 0.11-2.34 | 0.340 | 1.27 | 0.78-2.08 |
rs2239374 | 115 | 57 | 4 | 401 | 173 | 15 | 0.379 | 0.85 | 0.59-1.23 | 0.785 | 0.84 | 0.25-2.88 | 0.369 | 0.83 | 0.54-1.26 |
rs2286960 | 91 | 71 | 13 | 347 | 215 | 30 | 0.022 | 0.68 | 0.49-0.95 | 0.049 | 0.45 | 0.20-0.99 | 0.061 | 0.68 | 0.45-1.02 |
rs4251805 | 163 | 11 | 0 | 538 | 46 | 1 | 0.323 | 1.49 | 0.68-3.30 | ND | ND | ND | 0.340 | 1.48 | 0.66-3.30 |
rs344781 | 110 | 50 | 13 | 358 | 191 | 33 | 0.719 | 1.06 | 0.76-1.49 | 0.729 | 0.86 | 0.38-1.97 | 0.534 | 1.14 | 0.75-1.74 |
rs2356338 | 90 | 69 | 16 | 282 | 271 | 38 | 0.397 | 1.15 | 0.83-1.60 | 0.685 | 0.85 | 0.39-1.86 | 0.215 | 1.29 | 0.86-1.92 |
rs344780 | 107 | 42 | 11 | 341 | 180 | 31 | 0.611 | 1.10 | 0.77-1.56 | 0.729 | 0.86 | 0.36-2.06 | 0.422 | 1.197 | 0.77-1.86 |
rs344779 | 65 | 78 | 33 | 229 | 287 | 74 | 0.097 | 0.78 | 0.58-1.05 | 0.029 | 0.54 | 0.31-0.94 | 0.437 | 0.85 | 0.57-1.28 |
rs8113334 | 120 | 47 | 9 | 397 | 172 | 24 | 0.969 | 1.01 | 0.71-1.44 | 0.478 | 0.71 | 0.27-1.85 | 0.729 | 1.08 | 0.70-1.66 |
rs4493171 | 114 | 53 | 7 | 348 | 215 | 28 | 0.204 | 1.26 | 0.88-1.79 | 0.768 | 1.16 | 0.44-3.09 | 0.165 | 1.34 | 0.89-2.04 |
rs7259340 | 70 | 77 | 26 | 251 | 263 | 69 | 0.147 | 0.80 | 0.60-1.08 | 0.155 | 0.65 | 0.36-1.18 | 0.299 | 0.81 | 0.54-1.21 |
rs11668247Â | 67 | 68 | 41 | 241 | 267 | 87 | 0.034 | 0.74 | 0.56-0.98 | 0.022 | 0.55 | 0.34-0.92 | 0.172 | 0.75 | 0.50-1.13 |
rs346043 | 94 | 66 | 12 | 305 | 251 | 36 | 0.279 | 1.20 | 0.86-1.67 | 0.836 | 1.09 | 0.48-2.48 | 0.221 | 1.28 | 0.86-1.92 |
rs740587 | 54 | 72 | 50 | 206 | 272 | 110 | 0.010 | 0.70 | 0.53-0.92 | 0.016 | 0.56 | 0.35-0.90 | 0.056 | 0.66 | 0.43-1.01 |
rs346054 | 59 | 69 | 48 | 171 | 296 | 124 | 0.293 | 0.86 | 0.66-1.14 | 0.011 | 0.55 | 0.35-0.87 | 0.509 | 1.15 | 0.76-1.77 |