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Table 4 Independent Predictors of Median Plasma HDL-C Levels (N = 784)

From: Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis

Predictors

 

Coefficient

X2

p

Q

Sex (Female = 0, Male = 1)

-0.327

102.294

<0.001

<0.001

BMI (Kg/m2)

-0.015

34.576

<0.001

<0.001

DM (Yes = 1, No = 0)

-0.224

33.335

<0.001

<0.001

Smoking (Yes = 1, No = 0)

-0.153

17.824

<0.001

<0.001

Gene

SNP

Coefficient

X 2

p

Q

CETP

rs12149545

0.121

11.566

0.001

0.003

LPL

rs328

0.101

9.903

0.002

0.005

APOC2

rs228911

0.057

8.239

0.004

0.008

APOA5

rs3135506

-0.150

7.206

0.007

0.012

LIPC

rs36041167

-0.110

7.144

0.008

0.012

  1. Abbreviations: BMI: Body mass index; DM: Diabetes mellitus. CETP: Cholesteryl Ester Transfer; LPL: Lipoprotein Lipase; APOC2: Apolipoprotein C-II; APOA5: Apolipoprotein A-V; LIPC: Hepatic Lipase