| All | LCAS | TexGen | p |
N | 784 | 333 | 451 | --- |
Demographics | ||||
Age (years) | 59.3 ± 11.0 | 59.3 ± 7.7 | 59.2 ± 13.2 | 0.527 |
Male/Female (%) | 586/198 (75/25) | 281/52 (84/16) | 305/146 (68/32) | <0.001 |
Height (m) | 1.73 ± 0.09 | 1.74 ± 0.08 | 1.73 ± 0.10 | 0.328 |
Body weight (Kg) | 86.8 ± 18.8 | 84.9 ± 15.6 | 88.3 ± 20.7 | 0.006 |
Body mass index (Kg/m2) | 28.8 ± 5.5 | 28.1 ± 4.5 | 29.3 ± 6.1 | 0.001 |
Systolic blood pressure (mmHg) | 125.9 ± 19.3 | 124.5 ± 15.3 | 127.1 ± 21.8 | 0.029 |
Diastolic blood Pressure (mmHg) | 75.8 ± 11.9 | 76.7 ± 8.8 | 75.1 ± 13.7 | 0.028 |
Diabetes mellitus (%) | 117 (14.5) | 11 (3.3) | 106 (23.5) | <0.001 |
Smoker (%) | 137 (17.5) | 68 (20) | 69 (15) | 0.071 |
History of myocardial infarction (%) | 289 (36.9) | 131 (39) | 158 (35) | <0.001 |
Plasma Lipids levels | ||||
TC (mg/dl) | 200.1 ± 56.5 | 220.0 ± 24.5 | 185.2 ± 68.0 | <0.001 |
HDL-C (mg/dl) | 43.8 ± 13.9 | 43.8 ± 11.3 | 43.8 ± 15.5 | 0.671 |
LDL-C (mg/dl) | 123.9 ± 46.9 | 143.9 ± 19.9 | 107.5 ± 55.1 | <0.001 |
LDL-C/HDL-C | 3.02 ± 1.28 | 3.49 ± 0.91 | 2.65 ± 1.40 | <0.001 |
Triglyceride (mg/dl) | 169.7 ± 154.8 | 161.5 ± 57.1 | 175.8 ± 198.0 | 0.101 |
Plasma apolipoprotein levels (LCAS only) | ||||
N | Â | 333 | Â | Â |
Apolipoprotein A-I |  | 132.7 ± 27.4 |  |  |
Apolioprotein B |  | 134.4 ± 20.8 |  |  |
Apolipoprotein B/Apolioprotein A-I |  | 1.05 ± 0.26 |  |  |
Apolipoprotein C-III |  | 35.2 ± 32.8 |  |  |
Quantitative indices of severity of coronary atherolosclerosis (LCAS only) | ||||
N | Â | 289 | Â | Â |
Average baseline MLD (mm) |  | 1.68 ± 0.40 |  |  |
Mean number of coronary lesions |  | 2.99 ± 1.38 |  |  |
Number of subject with ≥ two coronary lesion (%) |  | 241 (83%) |  |  |
Mean number of coronary occlusions |  | 0.29 ± 0.55 |  |  |
Number of subject with ≥ one coronary |  | 72 (25%) |  |  |